Hypoallergenic Siberian Cats and Kittens

Saliva and Fur Fel d1 tests

 Siberian cats and Kittens

What is "hypoallergenic" where cats are concerned, and what are "reasonable expectations" for allergy sufferers at this time?

Feline allergen is a very small glycoprotein created in the salivary (saliva), lacrimal (tears), sebaceous (skin), and perianal glands. Salivary Fel d1 becomes airborne during grooming, sebaceous Fel d1 tends to be distributed across the fur, with the highest levels being found near the skin. Perianal glands secrete the allergen onto the feces. The highest concentration of Fel d1 is found in the perianal glands. 

Feline allergen (Fel d1) is found only in cats and accounts for up to 60% of cat allergies. Typical reactions to the allergen vary, but includes symptoms ranging from mild runny nose and itchy eyes, to severe reactions such as swollen eyes, hives or difficulty breathing. Individuals allergic to cats and not other animals are usually allergic only to Fel d1. The allergen is very potent and can remain in a home for six months after removal of the cat. 

Ongoing research show that all cats produce Fel d1, but the amounts are quite varied. Studies by Siberian Research have shown is a very strong correlation between the allergen level in saliva and the perceived allergic reaction in highly allergic individuals. Siberians with very low allergen levels pass this trait to some (but not all) of the kittens in the litter. 

Production and secretion of the Fel d1 allergen is controlled by hormones and stress. In normal cats, the highest levels are found an not neutered males. In very low-allergen Siberians, making them hypoallergenic kittens. The males and females have similar levels of Fel d1. Some of the lowest levels have been found in Siberian kitten males.



Saliva and Fur tests



Saliva Test Range for Adult Siberians is 0.25 to 16 mcg

  • 50% of Siberians saliva test below 2.5 mcg 
    15% of Siberians saliva test below 1.0 mcg
    4% of non Siberians saliva test below 2.5 mcg
    0.25% of non Siberians saliva test below 1.0 mcg



Fur Test Range for Adult Siberians is 20mcg - 400 mcg

  • 50% of Siberians fur test below 120 mcg
    15% of Siberians fur test below 40 mcg
    4% of non Siberians test below 120 mcg
    4% of non Siberians test over 400 mcg



  • When male cats are neutered they will give up to 50% less FelD1 hormone
  • and females cats are spayed they will give up to 25% less FelD1 hormone



Saliva Results for Siberians: 0.08 mcg - 27 mcg

  • Extremely low: 0.2 - 1.0
    Very low: 1.0 - 1.7
    Low level: 1.7 - 2.5
    Medium Low: 2.5 - 4
    Normal / High: 4 - 16
    Very High: 16 - 27



Fur Test Results for Siberians 7 mcg - 820 mcg

  • Extremely low: 10 - 40
    Very low: 40 - 80
    Low level: 80 - 120
    Medium Low: 120 - 200
    Normal / High: 200 - 400
    Very High: 400 - 820